Yes, AI automation can integrate with virtually any business system using modern integration frameworks and AI orchestration tools. We connect to: (1) Cloud SaaS tools with APIs—Salesforce, HubSpot, QuickBooks, Slack, Microsoft 365, Google Workspace, Shopify, Notion, Airtable, and 100+ others through native integrations and AI function calling, (2) Databases—MySQL, PostgreSQL, SQL Server, MongoDB, Snowflake, and other databases using direct connections, vector databases (Pinecone, Weaviate) for AI memory, (3) Legacy systems—older software without APIs using methods like database access, file exports, screen scraping, or AI-powered UI automation where necessary, (4) Email—Office 365, Gmail, or SMTP for sending, receiving, and processing email automatically with AI-powered understanding and response generation, (5) Spreadsheets and documents—Google Sheets, Excel, CSV, or any document format using OCR and multimodal AI for reading/writing data, and (6) Custom or proprietary software—through API development, webhooks, custom connectors, or AI agents that interact with your systems like a human would. Modern AI models like GPT-5 and Claude Opus 4 include function calling capabilities that make integration more flexible and intelligent. During discovery, we audit your technology stack and confirm integration feasibility before proceeding. In 10+ years, we've rarely encountered a system we couldn't integrate with—though sometimes legacy systems require creative approaches or interim data transformation steps.